This website uses cookies to give you the best experience. By continuing to use this website you are consenting to cookies being used. You can delete and block cookies from within your browsers settings. For more information please refer to our privacy and cookie policy page.



Scleroderma in childhood is rare and variable in clinical presentations. 

Localized scleroderma is the most common and can present at any age, with the appearance of a patch of abnormal skin (called morphoea) and which, when untreated, generally follows a course of active expanding disease, fibrosis and eventual softening with some “remission”.

The functional and cosmetic impact can be profound, as the lesions may interfere with growth of a limb and subcutaneous tissues (of the face or a limb). 

Systemic scleroderma is extremely rare in children and includes progressive diffuse fibrous changes of the skin and fibrous changes involving internal organs - most commonly lungs, gastrointestinal tract, heart and kidneys - with a significant mortality.

Systemic scleroderma is slowly progressive, has a guarded prognosis and requires potent immunosuppression. 

Management includes aggressive treatments (corticosteroids and methotrexate, as well as other immunosuppressives) with the aim of limiting severe disfigurement and disability.

The photograph below shows linear scleroderma with pigmented indurated lesions and the right foot is smaller than the left.


 The photograph below shows linear scleroderma with typical 'waxy' pigmented lesions over the foot.



Site Statistics

To date (end of May 2022) PMM has >1,086,978 hits and >454,640 users from 223 countries!

Short online courses

from Newcastle University, UK

e-resources from PMM

pmm for you

Please help us ensure pmm is as useful to you as possible by completing this short survey

complete survey