This website uses cookies to give you the best experience. By continuing to use this website you are consenting to cookies being used. You can delete and block cookies from within your browsers settings. For more information please refer to our privacy and cookie policy page.


Early diagnosis and treatment make a difference

The emergence of biologic agents, as well as earlier and more aggressive treatment approaches, has dramatically changed the way that JIA has been managed over the last 10 years. Many children will do very well on treatment and will go into disease remission. There has been a trend for several years to minimise exposure to systemic corticosteroids which can have side effects (growth retardation, osteoporosis, weight gain and skin changes [striae and hirsutism], cataracts and adrenal suppression). 

As soon as JIA is suspected, early referral to specialist teams facilitates prompt treatment and prevention of complications including joint damage, contractures and disability. Early diagnosis and prompt access to the multidisciplinary specialist care can dramatically improve clinical outcomes. 

Joint damage and growth abnormalities are common without an early diagnosis and access to effective treatmentsIn many parts of the world, where access to medicines is limited by cost or availability then such presentations and clinical features are still commonly observed. 

The photographs below show extensive joint swelling and deformity in the hands and wrists in polyarticular JIA. 


The photograph below shows a blind eye with cataract from JIA related chronic anterior uveitis. 

 The photograph below shows finger contractures, subluxation at the wrists due to chronic, untreated arthritis 

Site Statistics

To date (end of April 2022) PMM has >1,063,574 hits and >444,543 users from 223 countries!



Short online courses

from Newcastle University, UK

e-resources from PMM

pmm for you

Please help us ensure pmm is as useful to you as possible by completing this short survey

complete survey